@article{89886, keywords = {Bacterial Proteins, Escherichia coli, Transcription Factors, Gene Expression Regulation, Bacterial, Protein Biosynthesis, Escherichia coli Proteins, DNA-Binding Proteins, Sigma Factor}, author = {Gibson and Silhavy}, title = {SprE levels are growth phase regulated in a sigma(S)-dependent manner at the level of translation}, abstract = {

SprE regulates sigma(S) levels in response to nutrient availability by promoting ClpXP-mediated degradation. Paradoxically, we observe that SprE is similarly regulated, accumulating preferentially upon starvation. This regulation of SprE levels is sigma(S) dependent, altering SprE synthesis at the level of translation. Thus, we demonstrate that SprE and sigma(S) function within a regulatory feedback loop.

}, year = {2000}, journal = {J Bacteriol}, volume = {182}, pages = {4117-20}, month = {07/2000}, issn = {0021-9193}, doi = {10.1128/JB.182.14.4117-4120.2000}, language = {eng}, }