Protein Sorting Signals

Wolk, Fekkes, Boorsma, Huie, Silhavy, and Driessen. (1998) 1998. “PrlA4 Prevents the Rejection of Signal Sequence Defective Preproteins by Stabilizing the SecA-SecY Interaction During the Initiation of Translocation”. EMBO J 17 (13): 3631-9. doi:10.1093/emboj/17.13.3631.

Reference Link
Schatz, Bieker, Ottemann, Silhavy, and Beckwith. (1991) 1991. “One of Three Transmembrane Stretches Is Sufficient for the Functioning of the SecE Protein, a Membrane Component of the E. Coli Secretion Machinery”. EMBO J 10 (7): 1749-57.

Reference Link
Trun, and Silhavy. 1989. “The Genetics of Protein Targeting in Escherichia Coli K12”. J Cell Sci Suppl 11: 13-28. doi:10.1242/jcs.1989.supplement_11.2.

Reference Link
Trun, and Silhavy. (1987) 1987. “Characterization and in Vivo Cloning of PrlC, a Suppressor of Signal Sequence Mutations in Escherichia Coli K12”. Genetics 116 (4): 513-21. doi:10.1093/genetics/116.4.513.

Reference Link
Stader, Benson, and Silhavy. (1986) 1986. “Kinetic Analysis of LamB Mutants Suggests the Signal Sequence Plays Multiple Roles in Protein Export”. J Biol Chem 261 (32): 15075-80.

Reference Link
Benson, Hall, and Silhavy. 1985. “Genetic Analysis of Protein Export in Escherichia Coli K12”. Annu Rev Biochem 54: 101-34. doi:10.1146/annurev.bi.54.070185.000533.

Reference Link
Benson, and Silhavy. (1983) 1983. “Information Within the Mature LamB Protein Necessary for Localization to the Outer Membrane of E Coli K12”. Cell 32 (4): 1325-35. doi:10.1016/0092-8674(83)90313-6.

Reference Link
Emr, and Silhavy. (1982) 1982. “Molecular Components of the Signal Sequence That Function in the Initiation of Protein Export”. J Cell Biol 95 (3): 689-96. doi:10.1083/jcb.95.3.689.

Reference Link
Ferenci, and Silhavy. (1987) 1987. “Sequence Information Required for Protein Translocation from the Cytoplasm”. J Bacteriol 169 (12): 5339-42. doi:10.1128/jb.169.12.5339-5342.1987.

Reference Link
Stader, Gansheroff, and Silhavy. (1989) 1989. “New Suppressors of Signal-Sequence Mutations, PrlG, Are Linked Tightly to the SecE Gene of Escherichia Coli”. Genes Dev 3 (7): 1045-52. doi:10.1101/gad.3.7.1045.

Reference Link
Stader, and Silhavy. (1988) 1988. “A Progenitor of the Outer Membrane LamB Trimer”. J Bacteriol 170 (4): 1973-4. doi:10.1128/jb.170.4.1973-1974.1988.

Reference Link
Bieker, and Silhavy. (1990) 1990. “The Genetics of Protein Secretion in E. Coli”. Trends Genet 6 (10): 329-34. doi:10.1016/0168-9525(90)90254-4.

Reference Link
Bieker, Phillips, and Silhavy. (1990) 1990. “The Sec and Prl Genes of Escherichia Coli”. J Bioenerg Biomembr 22 (3): 291-310. doi:10.1007/BF00763169.

Reference Link
Phillips, and Silhavy. (1990) 1990. “Heat-Shock Proteins DnaK and GroEL Facilitate Export of LacZ Hybrid Proteins in E. Coli”. Nature 344 (6269): 882-4. doi:10.1038/344882a0.

Reference Link
Huie, and Silhavy. (1995) 1995. “Suppression of Signal Sequence Defects and Azide Resistance in Escherichia Coli Commonly Result from the Same Mutations in SecA”. J Bacteriol 177 (12): 3518-26. doi:10.1128/jb.177.12.3518-3526.1995.

Reference Link
Flower, Doebele, and Silhavy. (1994) 1994. “PrlA and PrlG Suppressors Reduce the Requirement for Signal Sequence Recognition”. J Bacteriol 176 (18): 5607-14. doi:10.1128/jb.176.18.5607-5614.1994.

Reference Link
Carlson, and Silhavy. (1993) 1993. “Signal Sequence Processing Is Required for the Assembly of LamB Trimers in the Outer Membrane of Escherichia Coli”. J Bacteriol 175 (11): 3327-34. doi:10.1128/jb.175.11.3327-3334.1993.

Reference Link
Cosma, Danese, Carlson, Silhavy, and Snyder. (1995) 1995. “Mutational Activation of the Cpx Signal Transduction Pathway of Escherichia Coli Suppresses the Toxicity Conferred by Certain Envelope-Associated Stresses”. Mol Microbiol 18 (3): 491-505. doi:10.1111/j.1365-2958.1995.mmi_18030491.x.

Reference Link
Danese, Oliver, Barr, Bowman, Rick, and Silhavy. (1998) 1998. “Accumulation of the Enterobacterial Common Antigen Lipid II Biosynthetic Intermediate Stimulates DegP Transcription in Escherichia Coli”. J Bacteriol 180 (22): 5875-84. doi:10.1128/JB.180.22.5875-5884.1998.

Reference Link
Silhavy. (1997) 1997. “Death by Lethal Injection”. Science 278 (5340): 1085-6. doi:10.1126/science.278.5340.1085.

Reference Link
Duguay, Amy Rizzitello, and Thomas Silhavy. (2002) 2002. “Signal Sequence Mutations As Tools for the Characterization of LamB Folding Intermediates”. J Bacteriol 184 (24): 6918-28. doi:10.1128/JB.184.24.6918-6928.2002.

Reference Link
Wu, Tao, Juliana Malinverni, Natividad Ruiz, Seokhee Kim, Thomas Silhavy, and Daniel Kahne. (2005) 2005. “Identification of a Multicomponent Complex Required for Outer Membrane Biogenesis in Escherichia Coli”. Cell 121 (2): 235-45. doi:10.1016/j.cell.2005.02.015.

Reference Link
Bowers, Christina Wilson, Fion Lau, and Thomas Silhavy. (2003) 2003. “Secretion of LamB-LacZ by the Signal Recognition Particle Pathway of Escherichia Coli”. J Bacteriol 185 (19): 5697-705. doi:10.1128/JB.185.19.5697-5705.2003.

Reference Link
Ureta, Alejandro, Robert Endres, Ned Wingreen, and Thomas Silhavy. (2007) 2007. “Kinetic Analysis of the Assembly of the Outer Membrane Protein LamB in Escherichia Coli Mutants Each Lacking a Secretion or Targeting Factor in a Different Cellular Compartment”. J Bacteriol 189 (2): 446-54. doi:10.1128/JB.01103-06.

Reference Link
Stelten, Johna, Filo Silva, Dominique Belin, and Thomas Silhavy. (2009) 2009. “Effects of Antibiotics and a Proto-Oncogene Homolog on Destruction of Protein Translocator SecY”. Science 325 (5941): 753-6. doi:10.1126/science.1172221.

Reference Link