SEC Translocation Channels

Wolk, Fekkes, Boorsma, Huie, Silhavy, and Driessen. (1998) 1998. “PrlA4 Prevents the Rejection of Signal Sequence Defective Preproteins by Stabilizing the SecA-SecY Interaction During the Initiation of Translocation”. EMBO J 17 (13): 3631-9. doi:10.1093/emboj/17.13.3631.

Reference Link
Schatz, Bieker, Ottemann, Silhavy, and Beckwith. (1991) 1991. “One of Three Transmembrane Stretches Is Sufficient for the Functioning of the SecE Protein, a Membrane Component of the E. Coli Secretion Machinery”. EMBO J 10 (7): 1749-57.

Reference Link
Silhavy, Thomas, and Angela Mitchell. (2019) 2019. “Genetic Analysis of Protein Translocation”. Protein J 38 (3): 217-28. doi:10.1007/s10930-019-09813-y.

Reference Link
Stader, Gansheroff, and Silhavy. (1989) 1989. “New Suppressors of Signal-Sequence Mutations, PrlG, Are Linked Tightly to the SecE Gene of Escherichia Coli”. Genes Dev 3 (7): 1045-52. doi:10.1101/gad.3.7.1045.

Reference Link
Trun, Stader, Lupas, Kumamoto, and Silhavy. (1988) 1988. “Two Cellular Components, PrlA and SecB, That Recognize Different Sequence Determinants Are Required for Efficient Protein Export”. J Bacteriol 170 (12): 5928-30. doi:10.1128/jb.170.12.5928-5930.1988.

Reference Link
Bieker, and Silhavy. (1990) 1990. “PrlA (SecY) and PrlG (SecE) Interact Directly and Function Sequentially During Protein Translocation in E. Coli”. Cell 61 (5): 833-42. doi:10.1016/0092-8674(90)90193-i.

Reference Link
Huie, and Silhavy. (1995) 1995. “Suppression of Signal Sequence Defects and Azide Resistance in Escherichia Coli Commonly Result from the Same Mutations in SecA”. J Bacteriol 177 (12): 3518-26. doi:10.1128/jb.177.12.3518-3526.1995.

Reference Link
Flower, Osborne, and Silhavy. (1995) 1995. “The Allele-Specific Synthetic Lethality of PrlA-PrlG Double Mutants Predicts Interactive Domains of SecY and SecE”. EMBO J 14 (5): 884-93.

Reference Link
Flower, Doebele, and Silhavy. (1994) 1994. “PrlA and PrlG Suppressors Reduce the Requirement for Signal Sequence Recognition”. J Bacteriol 176 (18): 5607-14. doi:10.1128/jb.176.18.5607-5614.1994.

Reference Link
Osborne, and Silhavy. (1993) 1993. “PrlA Suppressor Mutations Cluster in Regions Corresponding to Three Distinct Topological Domains”. EMBO J 12 (9): 3391-8.

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Bieker-Brady, and Silhavy. (1992) 1992. “Suppressor Analysis Suggests a Multistep, Cyclic Mechanism for Protein Secretion in Escherichia Coli”. EMBO J 11 (9): 3165-74.

Reference Link
Harris, and Silhavy. (1999) 1999. “Mapping an Interface of SecY (PrlA) and SecE (PrlG) by Using Synthetic Phenotypes and in Vivo Cross-Linking”. J Bacteriol 181 (11): 3438-44. doi:10.1128/JB.181.11.3438-3444.1999.

Reference Link
Stelten, Johna, Filo Silva, Dominique Belin, and Thomas Silhavy. (2009) 2009. “Effects of Antibiotics and a Proto-Oncogene Homolog on Destruction of Protein Translocator SecY”. Science 325 (5941): 753-6. doi:10.1126/science.1172221.

Reference Link
Grabowicz, Marcin, Jennifer Yeh, and Thomas Silhavy. (2013) 2013. “Dominant Negative LptE Mutation That Supports a Role for LptE As a Plug in the LptD Barrel”. J Bacteriol 195 (6): 1327-34. doi:10.1128/JB.02142-12.

Reference Link