Making a beta-barrel: assembly of outer membrane proteins in Gram-negative bacteria
Publication Year
2012
Type
Journal Article
Abstract
The outer membrane (OM) of Gram-negative bacteria is an essential organelle that serves as a selective permeability barrier by keeping toxic compounds out of the cell while allowing vital nutrients in. How the OM and its constituent lipid and protein components are assembled remains an area of active research. In this review, we describe our current understanding of how outer membrane proteins (OMPs) are delivered to and then assembled in the OM of the model Gram-negative organism Escherichia coli.
Keywords
Journal
Curr Opin Microbiol
Volume
15
Issue
2
Pages
189-93
Date Published
04/2012
ISSN Number
1879-0364
Alternate Journal
Curr Opin Microbiol
PMID
22221898